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Research Projects

Completed Research Projects:

  • Epigenetic regulation in breast cancer
  • Gene expression profiling in oral cancers: identification of potential prognostic markers using 50 Gene microarray NGS panel
  • To identify and quantify extravascular lung water volume by lung ultrasound in oncosurgical patients undergoingCRS and HIPEC under anaesthesia
  • Immunophenotyping of male breast cancer- experience at tertiary cancer care centre
  • Can the problem of harmonization of Ki67 scoring be solved through gene expression based (qRTPCR) methodology?
  • Concordance of qRTPCR for detection of HER2 neu amplification defined status in relation to IHC and FISH in Breast Cancer patients
  • Cell free nucleic acid detection of EGFR mutation in monitoring response and progression to secondary resistance in lung cancer patients
  • Correlation of MMR protein expression in endometrial cancer with its histological variants and its clinical relevance
  • Comparative evaluation of suspicious breast lesions by full field digital mammography (FFDM) versus dynamic contrast MRI with histopathological correlation
  • Role of circulating tumour cells to determine prognosis in metastatic breast cancer
  • Double hit and double expressor diffuse large B cell lymphoma:  comparison and clinico-pathological correlation of 100 Cases
  • Cardiac output monitoring:  A comparative study Of Conventional Cardiac Output Monitor Vigileo And The New Smartphone Based Application Capstesia
  • Stratification of High Grade Urothelial Carcinoma of Urinary Bladder into Molecular Subtypes (WHO 2016) by Immunohistochemical Stains and its Morphological and Clinical Correlation
  • Axillary lymph nodal evaluation on ultrasound in CA breast  and its correlation with surgery and histopathology
  • To determine the Prognostic Value of Circulating Tumor Cells in advanced Epithelial Carcinoma Ovary
  • BCR-ABL1 fusion Transcript Quantification in plasma by Droplet Digital PCR and RQPCR – A comparative Study
  • Hospital Based Cancer Registry in Sources of Registration of already existing PBCRs at Bangalore, Chennai, Delhi, Mumbai and Kolkata
  • A Multi-Centric Study For Sub-Classification Of Burkitt Lymphoma
  • A prospective single centre study to compare diagnostic performance of hepato-biliary phase MRI post administration of Gd-BOPTA with diffusion weighted MRI, extracellular phase dynamic MRI, FDG-PET and Triple Phase CT in evaluating patients for curative resection/ablation of colorectal liver metastasis
  • Androgen Receptor Expression in Triple Negative Breast Cancer – An Initial Experience
  • To study the role of pre treatment microRNA expression as a predictor of response to chemo-radiation in locally advanced carcinoma cervix
  • Patterns of radiological response with targeted molecular therapy in lung malignancies: feasibility of RECIST 1.1 criteria. A prospective analysis

Ongoing Research Projects:

  • Hospital Based Cancer Registry in Sources of Registration of already existing PBCRs at Bangalore, Chennai, Delhi, Mumbai and Kolkata
  • A Multi-Centric Study For Sub-Classification Of Burkitt Lymphoma
  • A prospective single centre study to compare diagnostic performance of hepato-biliary phase MRI post administration of Gd-BOPTA with diffusion weighted MRI, extracellular phase dynamic MRI, FDG-PET and Triple Phase CT in evaluating patients for curative resection/ablation of colorectal liver metastasis
  • Whole exome sequencing of Gall Bladder Cancer
  • Androgen Receptor Expression in Triple Negative Breast Cancer – An Initial Experience
  • To study the role of pretreatment microRNA expression as a predictor of response to chemoradiation in locally advanced carcinoma cervix
  • Patterns of radiological response with targeted molecular therapy in lung malignancies: feasibility of RECIST 1.1 criteria. A prospective analysis
  • Androgen receptor expression in triple negative breast cancers: a comparative study
  • Comparison of MMR protein status by IHC and MSI by PCR based Assay/ Sanger sequencing in right and left colonic adenocarcinoma
  • Analytical Comparisons of PDL-1 Assay SP142 and SP263 by Immunohistochemistry
  • A Prospective Study of Demographic Profile, Acute Toxicity and Early Tumour Control in Squamous Cell Carcinoma of Oropharynx Treated by Chemo-Radiotherapy With Specific Emphasis on Hpv Positivity
  • Sentinel lymph node mapping using indocyanine green and near – infrared fluorescence technology for uterine and cervical malignancies: our preliminary experience with the Da Vinci Xi System
  • Formulation and Clinical Evaluation of 177lu-Psma-617 In Docetaxel Refractory Metastatic Castration Resistant Prostate Cancer Patient
  • Objective Assessment of Patients stated Quality of Life following Surgery, Chemotherapy and Radiation Therapy in Early stage Breast Cancer Patients
  • Identification of Risk Factors Associated with Breast Cancer: A Matched Case-Control Study
  • Cross-sectional study to establish the utility of serum tumor markers in the diagnosis of lung cancer
  • Assessment of Oral Health Status of children with Leukemia
  • Comparison of pre-operative PEC-2 block, intra-operative PEC-2 block and opioid based general anaesthesia for post operative pain relief and PONV in patients undergoing modified radical mastectomy
  • Comparison of pre-incisional ultrasound guided PECS block and intra-operative PECS block under direct vision for post operative pain relief, operating surgical conditions, opioid requirements and PONV in patients undergoing modified radical mastectomy: a randomized controlled trial
  • Patterns of pleuro-pulmonary involvement in lymphoma
  • To assess survival and chemotherapy related toxicity profile in ovarian cancer patients

Research Projects in Pipeline

  • A Prospective Assessment of Deep Inspiration Breath-Hold for Left-Sided Breast Radiotherapy
  • Gastric Adenocarcinoma: Molecular Subtyping using Immunohistochemistry & its Clinicopathological & Therapeutic Implications
  • Chemotherapy impact on weight change and gastrointestinal symptoms in cancer patients : A pilot study from cancer centre in Northern India
  • “Concordance study of liquid and tissue-based Biomarker profile of Lung cancer by next-generation sequencing (NGS)”
  • Prognostic significance of evaluating PDL-1 and FOXP3 expression in HER2 positive breast cancer
  • CRS and HIPEC- An Improved Therapeutic Approach for Advanced Ovarian Cancer- A Retrospective Seven Year Study at Rgci, A Tertiary Care Cancer Center
  • Multicenter randomized study of number of nodes and passes during ebus-tbna in sarcoidosis (nopes) protocol
  • Can Cyclin D a surrogate marker for bladder cancer? A strategy to identify the prognosticator and a predictor
  • Population based cancer registeries at Chandigarh, SAS Nagar (Mohali),Sangrur and Mansa districts of the Punjab state Population based cancer registry at Varansi district, Uttar Pradesh

Collaborative Research Projects

S.No. Title Institute
1 Multi-centric Case Study on Carcinogenic and Non Carcinogenic Polycyclic Aromatic Hydrocarbons and its impact on Lung Cancer: Role of smoking and Occupational Exposure CSIR-Indian Institute of Toxicology Research, Lucknow
2 Molecular profiling to identify genetic signature in tobacco –induced oral cancer National Institute of Cancer Prevention and Research, NOIDA
3 Hospital Based Cancer Registry in Sources of Registration of already existing PBCRs at Bangalore, Chennai, Delhi, Mumbai and Kolkata National Centre for Disease Informatics and Research, Bangalore
4 Analysing the expression of putative androgen receptor in Prostate Tumor samples versus normal Prostate tissues Amity University, Gurugram
5 Mass Spectrometry Based Characterizations of Salivary Proteins for Early Detection of Ovarian Cancer Indian Institute of Technology Roorkee
6 Prognostic role of androgen receptor in triple negative breast cancers: A multi-Institutional experience Georgia State University,Atlanta, USA

 

 

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