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Dr. David K Simson

MBBS, DNB (Radiation Oncology)


Consultant – Gastrointestinal, Hepatopancreatobiliary, Genitourinary, Total Body Radiation Oncology Services

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Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India

About

Dr. David K Simson is a trained radiation oncologist specializing in advanced radiation techniques, including intensity-modulated radiotherapy (IMRT), image-guided radiotherapy (IGRT), volumetric modulated arc therapy (VMAT) / Rapid Arc, stereotactic body radiotherapy (SBRT), stereotactic radiotherapy (SRT), and stereotactic radiosurgery (SRS). He is also experienced in interstitial, intracavitary, and intraluminal brachytherapy.

Dr. Simson graduated from AIMS, Thrissur, and joined Rajiv Gandhi Cancer Institute in 2012 for his post-graduate training in radiation oncology. Following his training, he gained valuable experience working in various cancer hospitals in Delhi, including Action Cancer Hospital. Before rejoining his alma mater, he served as a consultant radiation oncologist at Fortis Hospital.

In 2017, Dr. Simson successfully cleared the European Society for Medical Oncology (ESMO) exam. He has a keen interest in teaching and research and is deeply involved in the institute’s postgraduate program. Dr. Simson has numerous publications in national and international peer-reviewed journals.

Dr. Simson is a member of various professional organisations, including the European Society for Medical Oncology (ESMO), the Association of Radiation Oncologists of India (AROI), and the Delhi Oncology Forum.

Currently, Dr. Simson is a consultant in Gastrointestinal, Hepatopancreatobiliary, Genitourinary, and Total-Body Radiation Oncology Services at Rajiv Gandhi Cancer Institute and Research Centre. His expertise includes using Tomotherapy for total-body irradiation (TBI) and the Cyberknife system for SBRT, SRT, and SRS.

Specialized Areas

  • Gastrointestinal cancers, including oesophagal, stomach, colon, rectal cancer and anal canal cancers
  • Hepatobiliary cancers, including pancreas, liver, cholangiocarcinoma, gall bladder, pancreatic, and periampullary cancers.
  • Genitourinary malignancies including prostate, urinary bladder, kidney or renal cell carcinoma, ureteric, and testicular cancers.
  • Total body irradiation before bone marrow transplantation on Helical Tomotherapy.
  • Stereotactic treatment of primary and metastatic lesions in the brain, lung, liver, pancreas, prostate, and spinal areas using the Cyberknife system, especially respiratory tracking for lung, liver, and pancreatic lesions.

Educational Background

  • M.B.B.S. 2004 batch – Amala Institute of Medical Sciences, Thrissur, Kerala.
  • D.N.B. Radiation Oncology, 2012 batch – Rajiv Gandhi Cancer hospital and research centre, New Delhi.
  • C.M.O: Cleared ESMO examination in September 2017.
  • Fellow of Royal College of Radiologists (FRCR): Passed 3 subjects (Radiobiology and molecular biology, clinical pharmacology and medical statistics) of Part 1 as of date.

Experience

  • 2004 – 2010: MBBS and internship at Amala Institute of Medical Sciences, Thrissur, Kerala.
  • 2011: Tutor in the Department of General Medicine at Karuna Medical College, Palakkad, Kerala.
  • 2012: PG Registrar in the radiation oncology department at Christian Medical College (CMC) Vellore.
  • 2012 – 2015: DNB Resident in the radiation oncology department at Rajiv Gandhi Cancer Institute and Research Centre, New Delhi.
  • 2014: Observership in the department of radiation at All India Institute of Medical Sciences, New Delhi.
  • 2015 – 2018: Action Cancer Hospital, Delhi; when leaving, he was a clinical associate.
  • 2018 – 2021: Fortis Hospital, Shalimar Bagh, Delhi; he was a consultant when he left.

Professional Journey

Achievements

  • Moderator for panel discussion on liver SBRT for hepatocellular carcinoma – Oncology Conundrums, New Delhi, May 2024
  • Panelist for a panel discussion on ‘Is ring gantry a real solution for TBI’, XXIX Annual conference of Association of Medical Physicists of India (Northern Chapter), New Delhi – April 2024
  • Debate on ‘SBRT versus ablation for pulmonary metastasis from colorectal malignancy’ Spoke in favour of SBRT, GI MDT, New Delhi, April 2024
  • Topic presentation – Role and duration of ADT in salvage treatment of prostate cancer, Society of Genitourinary Oncologists – SOGO, New Delhi, March 2024
  • Panelist for a panel discussion on ‘SBRT in cholangiocarcinoma – case-based discussion’, Midterm meeting of oncology forum, New Delhi – March 2024
  • Guest Faculty for a panel discussion on ‘Navigating the crossroads: SBRT vs Brachytherapy for liver metastasis’, 10th YROC, Jodhpur, India – January 2024
  • Panelist for a panel discussion on ‘Management of Her2+ve Metastatic Breast Cancer’, Oncology Review 2023, Faridabad, India – December 2023
  • Panelist for a panel discussion on ‘PinPoint Cases – Bladder Preservation for all?’, 3rd International Cancer Summit, New Delhi – October 2023
  • Moderator of the panel discussion on SRS/SRT in brain SOLs, 2nd Metro-OncoCon, New Delhi – June 2023
  • Debate on ‘adjuvant versus salvage radiotherapy in prostate cancer’ Spoke in favour of adjuvant radiotherapy, Delhi URO – Oncology Meeting, New Delhi, June 2023
  • Guest Faculty for a panel discussion on prostate cancer management, 9th YROC, Lucknow, India – February 2023
  • Master of the ceremony for Gyn oncology hall for 42nd AROICON national conference, New Delhi – December 2022
  • Poster presentation – Adenocarcinoma cervix, our last ten-year experience – ESMO gynecological cancers congress, Valencia, Spain – June 2022
  • Panel discussion moderator – EBRT contouring controversies in prostate cancer – RGCON 2022 – April 2022 Crown Plaza, New Delhi – April 2022
  • Panel discussion moderator – Molecular classification-based radiation treatment in endometrial cancer, Delhi Gyne Oncology Group (DGOG) – February 2022
  • Quiz Master – RADONC CONCLAVE, New Delhi – February 2022
  • Lecture – 1 hour session, know cancer better- cancer awareness campaign for general public – conducted by Centre for India Studies, Kuwait – 4th December 2020.
  • Panel discussion (Moderator)- Updates in management of GBM – 3rd September 2020.
  • Panelist-Recent updates in management of prostate cancer and covid 19 – 31st July 2020.
  • Topic presentation – Radical / SBRT for oligometastatic breast cancer – DBOG meet at Jaypee Hospital, Noida – February 2019.
  • Topic presentation – Local therapy for oligometastatic NSCLC, is there a benefit?. World Cancer congress, 29th April 2018, New Delhi, India.
  • Lecture – Re-Irradiation for recurrent head and neck cancer in the IMRT era. Medical Physics day lecture series. 7th Nov 2016, Nagarjuna Hospital, Vijayawada, India.
  • Poster presentation – Inderjit Kaur, Sheh Rawat, Gaurav Gupta, Upasna Sexana, Pooja Gogia, Aditi Tanwar, Manider Mishra, David K Simson; To measure interfractional variations in head and neck cancer patients by IGRT and its impact on dose volume histogram; 14th RGCON – Changing landscapes in head and neck oncology – future and beyond, Feb 2015, New Delhi, India.
  • Poster presentation – Sarthak Tandon, Sheh Rawat, Parveen Ahlawat, Manoj Pal, Gourav Gupta, Deepika Chauhan, David K Simson; A randomized study to compare IMRT using conventional fractionation schedule with IMRT using simultaneous modulated accelerated radiotherapy schedule in locally advanced head and neck cancers – An interim analysis; 14th RGCON – Changing landscapes in head and neck oncology – future and beyond, Feb 2015, New Delhi, India.
  • Trilateral debate on locoregional therapies in metastatic breast cancer – medical, surgical and radiation perspectives – Spoken in favour of “locoregional radiotherapy in metastatic carcinoma breast”. Delhi NCR Oncology Forum, 7th Jan 2015, New Delhi, India.
  • Oral Presentation – Predictive factors of pathological response to neoadjuvantchemoradiotherapy in locally advanced carcinoma rectum; 12th RGCON – “Changing Scenario in Colorectal Cancer”, Feb 2013, New Delhi, India.
  • Oral Presentation (during MBBS period) – Study of risk factors of coronary heart disease among adults aged above 25 years in rural communities in central Kerala; 53rd national conference of Indian public health association, Jan  2009, Bangalore, India.
  • Oral Presentation (during MBBS period) – Study on admission profile and outcome in medical intensive care unit in Central Kerala; 4th annual INDO-US Emergency Medicine Summit, Oct 2008, Mangalore, India.

Awards

  • First prize in soft tissue sarcoma quiz – 2nd international symposium on sarcoma management – April 2016
  • Silver medal for the final university (Calicut) exam in Obstetrics and Gynaecology subject.
  • Best paper presentation award (oral presentation category) in RGCON 2013.

Publications

  • Swarupa Mitra, David K Simson, Manish Gehani, Soumitra Barik, Ruparna Khurana, et al. Survival and Recurrence Patterns in Patients With Stomach Adenocarcinoma Receiving Chemotherapy or Chemoradiotherapy After D2 Gastrectomy in a Tertiary Care Cancer Institute: A Retrospective Real-World Evidence Cohort Study. Advances in Radiation Oncology. 2023;8(6).
  • David K Simson. Today’s Conviction, Tomorrow’s Mistake. Pract Radiat Oncol. 2022 Sep-Oct;12(5):e363-e364. doi: 10.1016/j.prro.2022.02.011. Epub 2022 Mar 7. PMID: 35272077.
  • Swarupa Mitra, David K Simson, Himanshi Khurana, Sarthak Tandon, Parveen Ahlawat, Nitin Bansal, Soumitra Barik, Jaskaran Singh Sethi, Kundan Singh Chufal, Munish Gairola. Treatment Delay during Radiotherapy of Cancer Patients due to COVID-19 Pandemic. Asian Pac J Cancer Prev. 2022 Jul 1;23(7):2415-2420. doi: 10.31557/APJCP.2022.23.7.2415. PMID: 35901349.
  • Sarthak Tandon, Parveen Ahlawat, Sunil Pasricha, Sandeep Purohit, David K Simson, Kiran Dobriyal, Preetha Umesh, Maninder Mishra, Lalit Kumar, Ahmed M Karimi, Jwala M, Munish Gairola. Depth of Invasion as an Independent Predictor of Survival in Patients of Stage III Squamous Cell Carcinoma of the Oral Tongue. Laryngoscope. 2022 Aug;132(8):1594-1599. doi: 10.1002/lary.29990. Epub 2021 Dec 16. PMID: 34918353.
  • Sukanya Semwal, Jaskaran Singh Sethi, Munish Gairola, David K Simson, Rajender Kumar, Ankit Goyal, Apoorv Vashistha, Ankit Kumar, Palak Goel. Evaluation of response rate of chemo-radiation and brachytherapy in patients with locally advanced carcinoma cervix in a tertiary care center. International Journal of Research in Medical Sciences. 2020 Mar; 8(4): 1361.
  • David K Simson, Swarupa Mitra, Parveen Ahlawat, Upasna Saxena, Manoj Kumar Sharma, Sheh Rawat, Harpreet Singh, Babita Bansal, Lalitha Kameshwari Sripathi, Aditi Tanwar; Prospective study of neoadjuvant chemoradiotherapy using IMRT and 5 Flurouracil for locally advanced rectal cancer – toxicities and response evaluation. Cancer Man Cancer Manag Res. 2018 Mar;10:519-526.
  • David K Simson, Sruthy P Kumar, Babita Bansal Singh, Lalitha Kameshwari, Parveen Ahlawat, S Prabhakar, Harpreet Singh, Manish Pandey, P Loganathan; Dosimetric comparison of Intensity Modulated Radiotherapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT) for Gastric cancer. Asian Journal of Radiation Oncology. 2017 Jan-Jun;1:10-17.
  • Lalitha Kameshwari, Parveen Ahlawat, David K Simson, Chiraranjan Khadanga, Lakshmipathi Kamarsu, Shital Kumar Surana, Harpreet Singh; Cardiac dose reduction with Deep-Inspiratory Breath Hold technique of radiotherapy for left sided breast cancer. J Med Phys. 2017 Jul-Sep; 42(3):123-127.
  • Parveen Ahlawat, Sheh Rawat, Anjali Kakria, Bharti Devnani, Inderjit Kaur Wahi, David K Simson; Reirradiation with IMRT for recurrent head and neck cancer: A single-institutional report on disease control, survival and toxicity. Rep Pract Oncol Radiother. 2017 Jul –Aug;22(4):331-339.
  • David K Simson; Conformal radiotherapy in rectal cancer: a dosimetric review. Int J Res Med Sci. 2017 Jan;5(1):08-12.
  • David K Simson, Swarupa Mitra, Parveen Ahlawat, Manoj Kumar Sharma, Girigesh Yadav, Maninder Bhushan Mishra; Dosimetric Comparison between Intensity Modulated Radiotherapy and 3 Dimensional Conformal Radiotherapy in the Treatment of Rectal Cancer. Asian Pac J Cancer Prev. 2016 Nov 1;17(11):4935-4937.
  • Swarupa Mitra, Anurag Mehta, Sunil Kumar Gupta, Anila Sharma, Robert Louis, Manoj Kumar Sharma, Upasna Saxena, David K Simson, Abhinav Dewan; Primary Gastric Burkitt’s Lymphoma – Case report and literature review. Rare Tumors. 2014 Oct 27; 6(4): 5300.
  • Manoj Kumar Sharma, Swarupa Mitra, Upasna Saxena, Maninder Bhushan, Himanshu Shrivastava, David K Simson, Abhinav Dewan, Deepika Chauhan; Is volumetric modulated arc therapy (RapidArc) better than intensity modulated radiotherapy for gynecological malignancies? A dosimetric comparison. J Cancer Res Ther. 2014 Oct-Dec;10(4):883-8.
  • Alvin George, Grace George, David K Simson, T P Antony.  A cross sectional analysis on the clinical presentation and outcome of H1N1 influenza patients in a tertiary care hospital in Central Kerala. International Journal of Advances in Medicine. 2019 Mar.6(2).
  • Aproorva Nayak, David K Simson, et al. Immunoscore-based wait-and-watch after short course radiation and chemotherapy in rectal cancer. Accepted for presentation at ESTRO 2024, Glasgow, UK
  • Varghese Antony, David K Simson, et al. Initial clinical and dosimetric outcomes with TBI planned on Helical Tomotherapy-Institutional Experience. Accepted for presentation at ESTRO 2024, Glasgow, UK
  • Arya Bhanu, Anjali Pahuja, David K Simson, et al. Comparing pathological response in bulky and non-bulky esophageal cancer after neoadjuvant treatment. Accepted for presentation at ESTRO 2024, Glasgow, UK
  • David K Simson, Swarupa Mitra, Himanshi Khurana, Soumitra Barik, Kiran Dobriyal, Athira Krishnan, et al. 10-year survival outcome and patterns of failure analysis of patients with localized adenocarcinoma cervix: Our experience from a tertiary cancer care center. Annals of Oncology. 2022;33:S386-S7.
  • Swarupa Mitra, Soumitra Barik, David K Simson, Kiran Dobriyal, Athira Krishnan, Jwala Mukhi, et al. Is Hypofractionated Elective Nodal Irradiation Safe in High-Risk Prostate Cancer? A Single-Institution Prospective Study. International Journal of Radiation Oncology, Biology, Physics. 2022;114(3):e231-e2.
  • Jwala Mukhi, Swarupa Mitra, Rahul Chowdhary, Moushmi Suryavanshi, David K Simson, Soumitra Barik, et al. A Technical Glitch or Whispers of Changing Epidemiology of HPV Negative Carcinoma Cervix? An Exploratory Study. International Journal of Radiation Oncology, Biology, Physics. 2022;114(3):e256
  • Jwala Mukhi, Swarupa Mitra, Rahul Chowdhary, Moushmi Suryavanshi, David K Simson, Soumitra Barik, et al. Prognostic Footprints of HPV Genotyping in Locally Advanced Carcinoma Cervix; A Single Institutional Study. International Journal of Radiation Oncology, Biology, Physics. 2022;114(3):e256-e7.
  • Swarupa Mitra, Manoj Kumar Sharma, Upasna Saxena, David K Simson, Manindra Mishra, Sabeena Kataria, Himanshu Srivastav; ‘Hopes and hypes with image-based brachytherapy: an indian experience with 53 patients. Can it be the standard yet?, Abstract publication. Asia Pac J Clin Oncol. 2014 Dec; 10:116.
  • David K Simson, Swarupa Mitra, Manoj Kumar Sharma, et al; A prospective study to evaluate the predictive factors, dosimetry and pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal carcinoma by conformal radiotherapy techniques. Abstract publication. Indian J Cancer. 2013 Nov;50(supplement1):S54.
  • David K Simson, Swarupa Mitra, Himanshi Khurana, Soumitra Barik, Kiran Dobriyal, Athira Krishnan, Preetha Umesh, Shilpa Pathi, Abhinav Dewan, 2022.10-year survival outcome and patterns of failure analysis of patients with localized adenocarcinoma cervix: Our experience from a tertiary cancer care center. Annals of Oncology 33, S386–S387.. doi:10.1016/j.annonc.2022.04.028

Membership

  • eLORA number: 16-03842
  • ESMO member: ID – 536694
  • Lifetime member of the Delhi Oncology Forum
  • Association of Radiation Oncologists’ of India (AROI): LM 1922
  • Travancore Cochin Medical Council – 42469
  • Tamilnadu Medical Council – 95814
  • Delhi Medical Council – 59473
  • Member of Continuing Medical Education-Thrissur Medical College Alumni Association (TMCAA)
  • Member of Alumni Association of Amala Institute of Medical Sciences (AIMSAAT)

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