Research Projects

Ongoing Research Projects:

• Breast Cancer in Young Women – Global Consortium (GCBCYW) : Globally Breast Cancer in young women is the biggest challenge. Rajiv Gandhi Cancer Institute & Research Centre in collaboration with  Lisbon Academic Medical Center, Portugal; Kyoto University, Japan; Young Survival Collation, New York USA; Team Shan, Canada; Tata Memorial, India; Himalayan Institute of Medical Sciences, India join hands in the fight against breast cancer in young women. Know More…
• Hospital Based Cancer Registry in Sources of Registration of already existing PBCRs at Bangalore, Chennai, Delhi, Mumbai and Kolkata
• A Multi-Centric Study For Sub-Classification Of Burkitt Lymphoma
• A prospective single centre study to compare diagnostic performance of hepato-biliary phase MRI post administration of Gd-BOPTA with diffusion weighted MRI, extracellular phase dynamic MRI, FDG-PET and Triple Phase CT in evaluating patients for curative resection/ablation of colorectal liver metastasis
• Whole exome sequencing of Gall Bladder Cancer
• Androgen Receptor Expression in Triple Negative Breast Cancer – An Initial Experience
• To study the role of pretreatment microRNA expression as a predictor of response to chemoradiation in locally advanced carcinoma cervix
• Patterns of radiological response with targeted molecular therapy in lung malignancies: feasibility of RECIST 1.1 criteria. A prospective analysis
• Androgen receptor expression in triple negative breast cancers: a comparative study
• Comparison of MMR protein status by IHC and MSI by PCR based Assay/ Sanger sequencing in right and left colonic adenocarcinoma
• Analytical Comparisons of PDL-1 Assay SP142 and SP263 by Immunohistochemistry
• A Prospective Study of Demographic Profile, Acute Toxicity and Early Tumour Control in Squamous Cell Carcinoma of Oropharynx Treated by Chemo-Radiotherapy With Specific Emphasis on Hpv Positivity
• Sentinel lymph node mapping using indocyanine green and near – infrared fluorescence technology for uterine and cervical malignancies: our preliminary experience with the Da Vinci Xi System
• Formulation and Clinical Evaluation of 177lu-Psma-617 In Docetaxel Refractory Metastatic Castration Resistant Prostate Cancer Patient
• Objective Assessment of Patients stated Quality of Life following Surgery, Chemotherapy and Radiation Therapy in Early stage Breast Cancer Patients
• Identification of Risk Factors Associated with Breast Cancer: A Matched Case-Control Study
• Cross-sectional study to establish the utility of serum tumor markers in the diagnosis of lung cancer
• Assessment of Oral Health Status of children with Leukemia
• Comparison of pre-operative PEC-2 block, intra-operative PEC-2 block and opioid based general anaesthesia for post operative pain relief and PONV in patients undergoing modified radical mastectomy
• Comparison of pre-incisional ultrasound guided PECS block and intra-operative PECS block under direct vision for post operative pain relief, operating surgical conditions, opioid requirements and PONV in patients undergoing modified radical mastectomy: a randomized controlled trial
• Patterns of pleuro-pulmonary involvement in lymphoma
• To assess survival and chemotherapy related toxicity profile in ovarian cancer patients

Completed Research Projects:

• Epigenetic regulation in breast cancer
• Gene expression profiling in oral cancers: identification of potential prognostic markers using 50 Gene microarray NGS panel
• To identify and quantify extravascular lung water volume by lung ultrasound in oncosurgical patients undergoingCRS and HIPEC under anaesthesia
• Immunophenotyping of male breast cancer- experience at tertiary cancer care centre
• Can the problem of harmonization of Ki67 scoring be solved through gene expression based (qRTPCR) methodology?
• Concordance of qRTPCR for detection of HER2 neu amplification defined status in relation to IHC and FISH in Breast Cancer patients
• Cell free nucleic acid detection of EGFR mutation in monitoring response and progression to secondary resistance in lung cancer patients
• Correlation of MMR protein expression in endometrial cancer with its histological variants and its clinical relevance
• Comparative evaluation of suspicious breast lesions by full field digital mammography (FFDM) versus dynamic contrast MRI with histopathological correlation
• Role of circulating tumour cells to determine prognosis in metastatic breast cancer
• Double hit and double expressor diffuse large B cell lymphoma:  comparison and clinico-pathological correlation of 100 Cases
• Cardiac output monitoring:  A comparative study Of Conventional Cardiac Output Monitor Vigileo And The New Smartphone Based Application Capstesia
• Stratification of High Grade Urothelial Carcinoma of Urinary Bladder into Molecular Subtypes (WHO 2016) by Immunohistochemical Stains and its Morphological and Clinical Correlation
• Axillary lymph nodal evaluation on ultrasound in CA breast  and its correlation with surgery and histopathology
• To determine the Prognostic Value of Circulating Tumor Cells in advanced Epithelial Carcinoma Ovary
• BCR-ABL1 fusion Transcript Quantification in plasma by Droplet Digital PCR and RQPCR – A comparative Study
• Hospital Based Cancer Registry in Sources of Registration of already existing PBCRs at Bangalore, Chennai, Delhi, Mumbai and Kolkata
• A Multi-Centric Study For Sub-Classification Of Burkitt Lymphoma
• A prospective single centre study to compare diagnostic performance of hepato-biliary phase MRI post administration of Gd-BOPTA with diffusion weighted MRI, extracellular phase dynamic MRI, FDG-PET and Triple Phase CT in evaluating patients for curative resection/ablation of colorectal liver metastasis
• Androgen Receptor Expression in Triple Negative Breast Cancer – An Initial Experience
• To study the role of pre treatment microRNA expression as a predictor of response to chemo-radiation in locally advanced carcinoma cervix
• Patterns of radiological response with targeted molecular therapy in lung malignancies: feasibility of RECIST 1.1 criteria. A prospective analysis

Research Projects in Pipeline

• A Prospective Assessment of Deep Inspiration Breath-Hold for Left-Sided Breast Radiotherapy
• Gastric Adenocarcinoma: Molecular Subtyping using Immunohistochemistry & its Clinicopathological & Therapeutic Implications
• Chemotherapy impact on weight change and gastrointestinal symptoms in cancer patients : A pilot study from cancer centre in Northern India
• “Concordance study of liquid and tissue-based Biomarker profile of Lung cancer by next-generation sequencing (NGS)”
• Prognostic significance of evaluating PDL-1 and FOXP3 expression in HER2 positive breast cancer
• CRS and HIPEC- An Improved Therapeutic Approach for Advanced Ovarian Cancer- A Retrospective Seven Year Study at Rgci, A Tertiary Care Cancer Center
• Multicenter randomized study of number of nodes and passes during ebus-tbna in sarcoidosis (nopes) protocol
• Can Cyclin D a surrogate marker for bladder cancer? A strategy to identify the prognosticator and a predictor
• Population based cancer registeries at Chandigarh, SAS Nagar (Mohali),Sangrur and Mansa districts of the Punjab state Population based cancer registry at Varansi district, Uttar Pradesh

Collaborative Research Projects