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Dr. Mayank Soni

MD, DrNB (Clinical Hematology)

Rajiv Gandhi Cancer Institute, Delhi, India

About

Dr. Mayank Soni is a Consultant Hematologist, Hemato-Oncologist, and Bone Marrow Transplant Physician with specialized training in Clinical Hematology and Hematopoietic Stem Cell Transplantation received from premier institutes of Delhi. His practice is dedicated to the diagnosis and management of the full spectrum of hematological disorders, ranging from benign blood diseases to complex hematological malignancies.

His areas of expertise include acute leukemias, lymphomas, multiple myeloma, myelodysplastic syndromes, bone marrow failure disorders, bleeding and thrombotic disorders, and cellular therapies. He has significant experience in autologous and allogeneic stem cell transplantation and is actively involved in advanced cellular therapies and comprehensive transplant care.

Dr. Soni is committed to delivering compassionate, patient-centered care through precision diagnostics, multidisciplinary collaboration, and evidence-based treatment. His academic interests include clinical research, translational hematology, and the integration of innovative therapies into routine clinical practice, with the overarching goal of improving survival and quality of life for patients with hematological diseases. His academic career is decorated with various achievements throughout his tenure.

Specialized Areas

  • Hematologic Malignancies
  • Acute and Chronic Leukemias
  • Lymphoma Management
  • Multiple Myeloma
  • Bone Marrow Failure Syndromes
  • Bone Marrow Transplantation (Autologous & Allogeneic)
  • Haploidentical Transplantation
  • Graft-versus-Host Disease Management
  • Cellular Therapy CAR-T cell therapy
  • Clinical Research and Trials

Educational Background

  • Doctorate National Board (DrNB) Clinical Hematology RGCIRC, Delhi
  • Fellowship in Haploidentical Hematopoietic Stem Cell Transplant and Cellular therapies, Dharamshila Narayana Super-speciality Hospital, Delhi
  • Fellowship Clinical Hematology Dharamshila Narayana Super-speciality Hospital, Delhi
  • Doctor of Medicine (MD) Jawaharlal Nehru Medical College, AMU, Aligarh
  • Bachelor of Medicine and Bachelor of Surgery (MBBS) University College of Medical Science and Guru Teg Bahadur hospital, Delhi

Experience

  • Consultant, Hemat-Oncology, RGCIRC, Delhi: 2025 – till date
  • Resident, Clinical Hematology, Rajiv Gandhi Super-Speciality Hospital, Tahirpur, Delhi: 2022 – 2025
  • Fellow, Bone Marrow Transplantation, Dharamshila Narayana Superspeciality Hospital, Delhi: 2020 – 2022
  • Fellow, Clinical Hematology Dharamshila Narayana Superspeciality Hospital, Delhi: 2018 – 2020
  • Senior Resident Hematology, ESI Basaidarapur, Delhi: 2015-2018

Professional Journey

Achievements and Awards
  • University Gold Medal, awarded for achieving University distinction in Doctor of Medicine Jawaharlal Nehru Medical College, AMU, Aligarh
  • Best Resident Award, Rajiv Gandhi Cancer Research Institute (2024) – Awarded in recognition of outstanding clinical performance and academic contributions during the DrNB Clinical Hematology
  • Second Prize, awarded during National Quiz Hematology Conclave 2024 – “Updates from EBMT 2024,” Glasgow
  • Second Prize, awarded during National Quiz Hematology Express Quiz – “Essence from ASH 2023,” 2024
Publication
  • Halder R, Singh R, Rainchwar S, Bhatnagar S, Tikare N, Palatty R, Singh A, Soni M, Tripathi S, Panda T, Sheth V, Ahmed R, Agrawal N, Bhurani D. Response-adapted dasatinib de-escalation strategy compared to upfront Low-dose dasatinib: A prospective cohort study. Leuk Res. 2026 Jun;165:108218. doi: 10.1016/j.leukres.2026.108218. Epub 2026 Mar 28. PMID: 41932299.
  • Soni M, Singh R, Rainchwar S, Bhatia N, Sarpal G, Pillai RH, Singh A, Bhatnagar S, Sheth VS, Agrawal N, Bhurani D, Halder R. Matched Unrelated Donor (MUD) Transplants Show Promising Outcomes in Thalassemia Patients Aged ≤ 12 Years. Hemoglobin. 2026 Mar;50(2):132-140. doi: 10.1080/03630269.2026.2632167. Epub 2026 Mar 2. PMID: 41772795.
  • Soni M, Goyal S, Agrawal N, Panda T. Anti‐donor antibody neutralization by donor type red cell challenge: A novel therapeutic strategy in refractory post‐transplant pure red cell aplasia. Transfusion. 2024 Sep;64(9):1798-800.
  • Sujay Rainchwar, Faran Naim, Tribikram Panda, Mohd Rizwan Shaikh, Rashmi Chand, Mayank Soni, Rohan Halder, Dinesh Bhurani, Narendra Agrawal, Rayaz Ahmed. Haploidentical HSCT With Fludarabine, Melphalan 75 mg/m2 and 400 cGy TBI: A Tolerable Conditioning Regimen With Low Toxicity and Good Anti-Leukemic Activity, Clinical Lymphoma Myeloma and Leukemia, Volume 24, Supplement 1, 2024.
  • Tribikram Panda, Sujay Rainchwar, Reema Singh, Aakanksha Singh, Mayank Soni, Dinesh Bhurani, Narendra Agrawal. Real world outcome of B ALL with t (1; 19) (q23; p13)/TCF3::PBX1 in adolescents and adults treated with intensive regimes, Leukemia Research, Volume 141, 2024.
  • Jaiswal SR, Arunachalam J, Bhardwaj A, Saifullah A, Lakhchaura R, Soni M, Bhagawati G, Chakrabarti S. Impact of adaptive natural killer cells, KLRC2 genotype and cytomegalovirus reactivation on late mortality in patients with severe COVID-19 lung disease. Clin Transl Immunology. 2022 Jan 11;11(1):e1359. doi: 10.1002/cti2.1359. PMID: 35035954; PMCID: PMC8752325.
  • Jaiswal SR, Bhakuni P, Bhagawati G, Aiyer HM, Soni M, Sharma N, Jaiswal RR, Chakrabarti A, Chakrabarti S. CTLA4Ig-primed donor lymphocyte infusions following haploidentical transplantation improve outcome with a distinct pattern of early immune reconstitution as compared to conventional donor lymphocyte infusions in advanced hematological malignancies. Bone Marrow Transplantation. 2021 Jan;56(1):185-94.
  • Jaiswal SR, Chakraborty S, Lakhchaura R, Sashi P, Mehta A, Soni M, Chakrabarti S. Early and Sustained Expansion of Adaptive Natural Killer Cells Following Haploidentical Transplantation and CTLA4Ig-Primed Donor Lymphocyte Infusions Dissociate Graft-versus-Leukemia and Graft-versus-Host Effects. Transplantation and Cellular Therapy 2020 Dec 21.
  • Jaiswal SR, Bhagwati G, Soni M, Thatai A, Aiyer H, Chakrabarti S. Prophylactic oseltamivir during major seasonal influenza H1N1 outbreak might reduce both H1N1 and associated pulmonary aspergillosis in children undergoing haploidentical transplantation. Transplant Infectious Disease. 2020 Oct;22(5):e13309.
  • Jaiswal SR, Bhakuni P, Soni M, Gupta M, Thatai A, Chakrabarti S. Safety and efficacy of Sofosbuvir and Velpatasvir in children with active hepatitis C virus infection undergoing haploidentical transplantation. Transplant Infectious Disease. 2020 Oct 10:e13490.
  • Soni M, Kaur O, Goswami S. Case report Adenosquamous Carcinoma of Gallbladder: A Large Sized Tumor Rarely Compatible with Life Indian Journal of Basic and Applied Medical Research; December 2016: Vol.-6, Issue- 1, P. 505-508.
  • Akhtar K, Arif SH, Soni M, Rana S, Siddiqui S. Metastatic granulosa cell tumor of the ovary-A cytologic disposition. Journal of Case Reports in Oncology and Therapy 2016 Mar 10;2(1).
  • Afroz N, Shamim N, Jain A, Soni M. Coexistence of giant cell fibroblastoma and encephalocele. BMJ Case Rep. 2014 Apr 11;2014:bcr2013203420. doi: 10.1136/bcr-2013-203420. PMID: 24728899; PMCID: PMC3987552.
  • Chaurasia JK, Soni M, Ahmed M, Naim M. White-blue pyelocalyceal cyst with hydrotic glomerulonephritis. BMJ Case Rep. 2013 Dec 17;2013:bcr2013201180. doi: 10.1136/bcr-2013-201180. PMID: 24347451; PMCID: PMC3888538.
Chapters in book
  • Novel strategies for drug delivery in hypoxic tumor: Cancer Hypoxia: Implication in Therapeutics and Precision Oncology
  • Breast cancer classification, serum adiponectin and SNP rs 2241766: Female breast duct carcinoma types, Serum adiponectin and SNP 45T/G rs2241766. ISBN 978- 3659522369. Naim, Mayank,

Membership

  • Member-The Indian Myeloma Academic Group (IMAGe)
  • Member-Society of Hematogic Oncology Woodlands USA