Dr. Rohan Halder

MBBS, MD, DM (Clinical Hematology), PDCC (Haemato-Oncology)

Consultant, Department of Haemato-Oncology & Bone Marrow Transplant

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Rajiv Gandhi Cancer Institute, Sector - 5, Rohini, Delhi - 110 085

About

Dr. Rohan Halder is erudite in managing Haemato-oncological diseases. He has more than 10 years’ experience in managing Haemato-Oncological conditions.

He is abreast in the updates in management of hematological conditions and its complications.

He has experience in performing bone marrow transplants-

Autologous BMT
Allogeneic BMT- Matched sibling transplant, Matched unrelated donor transplant, Haploidentical transplant
BMT for autoimmune conditions like multiple sclerosis, stiff person syndrome, myasthenia gravis.
Autoimmune Rheumatological conditions.
Chimeric antigen T Cell therapy- CAR T cell therapy for ACL & NHL

Specialized Areas

Acute Myeloid and Lymphoid Leukemias
Chronic Lymphocytic and Myeloid Leukemias
Aplastic Anemia and Bone Marrow Failure Syndromes
Myeloproliferative Neoplasms and Myelodysplastic Syndromes
High Dose Therapy with Stem Cell Rescue
Allogeneic Bone Marrow Transplant for Benign and Malignant Diseases
Histiocytic disorders

Educational Background

D.M (Clinical Hematology)

All India Institute of Medical Sciences, Department of Hematology, New Delhi

Year of commencement-2016
Year of completion-2019

Post-Doctoral Certificate Course (PDCC) -Hemato-Oncology

Sanjay Gandhi Post Graduate Institute of Medical Sciences, Department of Hematology, Lucknow

Year of commencement- 2014
Year of completion- 2015

M.D (Pediatrics)

VMMC and Safdarjung Hospital, Department of Pediatrics,New Delhi

Guru Gobind Singh Indraprastha University, New Delhi.

Year of commencement- 2010
Year of completion- 2013

Bachelor of Medicine and Surgery (M.B.B.S)

Sri Siddhartha Medical College, Tumkur, Karnataka

Rajiv Gandhi University of Health Sciences, Bangalore.

Year of commencement-2003
Year of completion- 2008

Experience

Consultant RGCI and RC, Hemato- Oncology from 2021
Worked as Associate Consultant in Department of Hemato-Oncology & Bone marrow transplant, Artemis Hospitals, Gurugram, Haryana from 08.07.2019 onwards till 31.03.2021.
Worked as Senior Resident (D.M) in Department of Hematology at All India Institute of Medical Sciences, New Delhi; Year of commencement- 2016; Date of completion- 04.07.19
Worked as Senior Resident Hospital Services and Post-Doctoral Certificate Course (Hemato-Oncology) in the Department of Hematology at, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Year of commencement- 2014; Year of completion- 2016
Worked as Senior Resident in the Department of Pediatrics at, VMMC and Safdarjang Hospital, New Delhi, Year of commencement- 2013; Year of completion- 2014

Professional Journey

Achievements

Performed the only allogeneic BMT for pediatric aplastic anemia with concomitant HIV infection in India.

Awards

Received distinction in Microbiology in M.B.B.S.
Received distinction in Pharmacology in M.B.B.S.
Received Indian Council of Medical Research (ICMR) grant for DM project in 2017 “To study the procalcitonin dynamics and its relation to bacterial and fungal infections in patients of febrile neutropenia.”

Publication

Research paper entitled 25 hydroxy cholecalciferol levels in infants with hypocalcemic seizures in Journal of Nutrition & Food sciences 2014, vol.4, issue 3 as corresponding author.
Case report entitled post varicella endocarditis complicating as cerebral abscess in Journal of Pediatric Infectious Diseases 2015, vol. 10 as corresponding author & first author.
Case report titled warm antibody autoimmune hemolytic anemia- a rare presentation of neonatal lupus in Lupus journal August 2016
Case report titled hodgkins lymphoma with central nervous system disease at primary presentation in Pediatric Blood and Cancer
Case report titled pulmonary lch- a not so benign lesion in Journal of Pediatric Hematology and Oncology
Brief report titled outcome of pediatric paroxysmal nocturnal hemoglobinuria in a resource constrainted setting in Pediatric Blood and Cancer.
Research paper titled pediatric myelofibrosis: who 2024 update on myeloproliferative neoplasms calling? In Pediatric Blood and Cancer.
Case report titled pediatric chronic pancreatitis due to metabolic disease: a rare etiology in Pancreas Journal.
Case report titled concomitant existence of paroxysmal nocturnal hemoglobinuria in a patient with hb E trait in Hemoglobin Journal.
Research paper titled clinical profile of bacterial meningitis in children and comparative inter-alia analysis of various microbiological tests in Journal of Child Science.
Research paper titled comparison of crp and procalcitonin for etiological diagnosis of fever during febrile neutropenia in hematology patients- an experience from a tertiary care center in northern india in Blood cells, Molecules and Diseases.
Research paper titled clinico-hematological profile of paroxysmal nocturnal hemoglobinuria in indian patients: flaer flow cytometry-based experience from an indian tertiary care centre in Indian Journal of Hematology and Blood Transfusion.
Case report titled proteoglycan induced coagulopathy in myeloma- a rare phenomenon in Leukemia and Lymphoma Journal.
Research paper titled proportion of cd34+cd38−cd123+ leukemia stem cells at diagnosis varies in ELN risk groups and an emerging novel marker for prognosticating the intermediate risk patients of acute myeloid leukemia: a prospective study in Indian Journal of Hematology and Blood Transfusion.
Panda T, Rainchwar S, Singh R, Singh A, Soni M, Kakkar D, Jegan KR, Pillai RH, Palatty RJ, Jha K, Ahmed R. “Real world outcome of B ALL with t (1; 19)(q23; p13)/TCF3:: PBX1 in adolescents and adults treated with intensive regimes.” Leukemia Research. 2024 Jun 1;141:107506. April 2024.
Mehta P, Singh A, Halder R, Jain A, Agrawal N, Ahmed R, Bhurani D. Hemophagocytic Lymphohistiocytosis (HLH): A Rare Cause of Primary Engraftment Failure Post Autologous Stem Cell Transplant. South Asian J Cancer. 2023 Aug 12;12(3):229-232.
Singh R, Kapoor J, Panwar N, Rainchwar S, Patra PC, Halder R, Ahmed R, Agrawal N, Bhurani D. HIV Associated Lymphomas: A Double-Edged Sword. Indian J Hematol Blood Transfus. 2024 Jan;40(1):146-149.
Bansal N, Sachdeva N, Bhurani D, Agarwal N, Halder R, Goyal P. Candida Empyema in Febrile Neutropenia – Augmented value of direct inoculation into BacT/Alert blood culture vials. Indian J Med Microbiol. 2022 Jul- Sep;40(3):440-442.
Halder R, Mishra V, Panda T, Agrawal N, Bhurani D. Defibrotide prophylaxis for prevention of sinusoidal obstruction syndrome. Lancet Haematol. 2023 Jul;10(7):e487.
Zaheir AS, Halder R, Nair RR, Singh PK, Bhar VS, Gambhir I, Zaheir NA. Proteoglycan induced coagulopathy in myeloma – a rare phenomenon. Leuk Lymphoma. 2021 Feb;62(2):492-494.
Rainchwar S, Halder R, Singh R, Mehta P, Verma M, Agrawal N, Ahmed R, Bhurani D, Bansal N. Pneumocystis jirovecii pneumonia [PJP]: An unrecognized concern in AML patients on Venetoclax. Leuk Res. 2022 Oct;121:106926.
Mishra P, Halder R, Aggarwal M, Seth T, Mahapatra M, Pati HP, Saxena R, Tyagi S. Pediatric myelofibrosis: WHO 2024 update on myeloproliferative neoplasms calling? Pediatr Blood Cancer. 2020 May;67(5):e28232.
Singh A, Halder R, Mishra V, Panda T, Agrawal N, Bhurani D. Myasthenia Gravis: A Rare and Unusual Side Effect of Long Term Desferral Chelation. Indian J Pediatr. 2023 Oct;90(10):1057
Mukherjee A, Rainchwar S, Singh A, Halder R, Patra PC, Ahmed R, Bhurani D, Agrawal N. Clinico-pathological features and treatment outcomes of high-grade B cell lymphoma-a tertiary cancer center experience. Blood Res. 2023 Dec 31;58(4):240-242.
Mehta P, Singh A, Halder R, Verma M, Agrawal N, Ahmed R, Bhurani D. Immunosuppression Boost With Mycophenolate Mofetil for Mixed Chimerism in Thalassemia Transplants. Transplant Cell Ther. 2023 Feb;29(2):122.e1-122.e6.
Halder R, Malik R, Kashyap R. Warm antibody hemolytic anemia-a rare presentation of neonatal lupus. 2017 May;26(6):661-663.
Halder R, Mishra P, Aggarwal M, Mannivanan P, Dhawan R, Seth T, Tyagi S, Mahapatra M, Pati HP, Saxena R. Outcomes of paroxysmal nocturnal hemoglobinuria in the pediatric age group in a resource-constrained setting. Pediatr Blood Cancer. 2020 Apr;67(4):e27712.
Ahmed R, Singh R, Kapoor J, Chandra Patra P, Agrawal N, Bhurani D, Halder R. Attenuated Dose Dasatinib in Newly Diagnosed Chronic Myeloid Leukemia Chronic Phase Patients in India. Clin Lymphoma Myeloma Leuk. 2023 Feb;23(2):e71-e77.
Mehta P, Kapoor J, Singh A, Yadav N, Singh R, Halder R, Verma M, Agrawal N, Ahmed R, Bhurani D. Busulfan and cyclophosphamide-based conditioning regimen still holds the promise of being a safe and efficacious regimen for allogeneic transplantation in patients with transfusion-dependent thalassemia, even in high risk. Eur J Haematol. 2022 Nov;109(5):447-457.
Patra PC, Rainchwar S, Singh R, Halder R, Mehta P, Verma M, Ahmed R, Raichaudhuri JS, Bhurani D, Agrawal N, Pramanik S. End of induction MRD assessment based early treatment intensification with novel agents in ETP-ALL- may be the way forward. Blood Res. 2023 Jun 30;58(2):112-115
Bansal N, Sachdeva N, Bhurani D, Agarwal N, Ahmed R, Mehta P, Halder R. Effect of antibiotic de-escalation on clinical outcomes in patients with carbapenem-resistant Enterobacteriaceae bacteremia (CRE) in the hematology- oncology setting. Germs. 2023 Sep 30;13(3):221-228.
Halder R, Anantharaman MB, Seth T, Mahapatra M, Saxena R. Pulmonary Langerhans Cell Histiocytosis: A not so Benign Lesion. J Pediatr Hematol Oncol. 2019 Mar;41(2):e122-e124.
Mishra P, Tripathi P, Halder R, Saxena R, Tyagi S, Mahapatra M, Pati HP. Clinico-Hematological Profile of Paroxysmal Nocturnal Hemoglobinuria in Indian Patients: FLAER Flow Cytometry Based Experience from an Indian Tertiary Care Centre. Indian J Hematol Blood Transfus. 2021 Apr;37(2):220-225.
Mishra P, Tyagi S, Sharma R, Halder R, Pati HP, Saxena R, Mahapatra M. Proportion of CD34+ CD38− CD123+ Leukemia Stem Cells at Diagnosis Varies in ELN Risk Groups and an Emerging Novel Marker for Prognosticating the Intermediate Risk patients of Acute Myeloid Leukemia: A Prospective Study. Indian Journal of Hematology and Blood Transfusion. 2021 Jul;37:391-7.
Panda D, Tejwani N, Pandey P, Mehta A, Rainchwar S, Panda T, Halder R, Palatty RJ, Agrawal N, Bhurani D. Myeloid sarcoma with RAM phenotype in an adult male presenting with CNS relapse; no longer a pediatric disease. Ann Hematol.2024 Apr 27.
Shaikh MR, Singh B, Halder R, Singh R, Shaikh MR, Agarwal N, Bansal N, Ahmed R, Mirgh SP, Bhurani D. FLAG based v/s Standard 3 + 7 induction therapy in treatment naïve Acute Myeloid Leukemia: Time to think “beyond anthracyclines”. Leuk Res. 2023 Sep;132:107346.
Halder R, Seth T, Chaturvedi PK, Mishra P, Mahapatra M, Pati HP, Tyagi S, Saxena R. Comparison of CRP and procalcitonin for etiological diagnosis of fever during febrile neutropenia in hematology patients- an experience from a tertiary care center in Northern India. Blood Cells Mol Dis. 2020 Sep;84:102445.
Panda T, Rainchwar S, Halder R, Singh R, Bhurani D, Agrawal N. Low fixed dose pembrolizumab with gemcitabine, vinorelbine, liposomal doxorubicin (Pembro100 -GVD) as an effective salvage regimen in relapsed refractory classical hodgkin’s lymphoma and primary mediastinal B cell lymphoma. Ann Hematol. 2024 Jan;103(1):347-349.
Panda T, Rainchwar S, Singh R, Singh A, Soni M, Kakkar D, Jegan KR, Pillai RH, Palatty RJ, Jha K, Ahmed R, Halder R, Tejwani N, Panda D, Bhurani D, Agrawal N. Real world outcome of B ALL with t (1; 19) (q23; p13)/TCF3::PBX1 in adolescents and adults treated with intensive regimes. Leuk Res. 2024 Jun;141:107506.
Halder R, Sundaram UK, Veetil KK, Rath A, Seth T, Tyagi S, Pati HP. Concomitant Existence of Paroxysmal Nocturnal Hemoglobinuria in a Patient with Hb E (HBB: c. 79G> A) Trait. Hemoglobin. 2020 Mar 3;44(2):134-6.
Halder R, Kashyap R. Hodgkin Lymphoma With Central Nervous System Disease at Primary Presentation. Pediatr Blood Cancer. 2016 Jun;63(6):1130.
Malik R, Halder R. Pediatric Chronic Pancreatitis Due to Metabolic Disease: A Rare Etiology. 2017 May/Jun;46(5):e42-e43.
Singh R, Soni M, Rainchwar S, Bhatia N, Palatty RJ, Jha K, Panda T, Agrawal N, Bhurani D, Halder R. Matched Unrelated Donor (MUD) Hematopoietic Stem Cell Transplant in Thalassemia Patient: An Outcome-Based Analysis of Pediatric Cohort in Tertiary Cancer Care Centre of North India. Transplantation and Cellular Therapy, Official Publication of the American Society for Transplantation and Cellular Therapy. 2024 Feb 1;30(2):S300-1.
Singh R, Rainchwar S, Halder R, Bhatia N, Jha K, Panda T, Ahmed R, Bhurani D, Agrawal N. Casting Hope, Defying Odds: Unveiling the Impact of Haplo-Identical Stem Cell Transplant in Myeloid Malignancies-a Tertiary Cancer Care Center Experience. Blood. 2023 Nov 28;142:6983.
Halder R, Pillai RH, Gupta VH, Rainchwar S, Jha K, Panda T, Ahmed R, Agrawal N, Singh R, Bhurani D. Allogeneic Stem Cell Transplant for High-Risk Transfusion Dependent Thalassemia [Tdt]-a Comparative Analysis of Flu/Bu/Cy/ATG Versus Flu/Thio/Treo Regimen. Blood. 2023 Nov 28;142:4961.
Singh A, Singh R, Halder R, Jha K, Panda T, Maroof AK, Bhatia N, Ahmed R, Bhurani D, Agrawal N. Risk and Response Adapted Approach for Treatment of Myeloma: Pushing Autologous Transplant Down the Hierarchy. Blood. 2023 Nov 28;142:3600.
Shaikh MR, Singh B, Singh R, Halder R, Jha K, Panda T, Ahmed R, Agrawal N, Bhurani D. A Retrospective Comparative Analysis of Intensive Vs. Non-Intensive Chemotherapy in Treatment Naïve Acute Myeloid Leukemia (AML) Patients in India. 2023 Nov 28;142:5842.
Rainchwar S, Panda T, Singh R, Jegan KR, Goswami S, Pillai RH, Kakkar D, Soni M, Singh A, Halder R, Ahemad R. ALL-215 Improved Outcomes of Acute Lymphoblastic Leukemia (ALL) in Adolescent and Young Adults (AYA) Treated With Modified COG0232, a Paediatric-Inspired Intensive Regimen. Clinical Lymphoma Myeloma and Leukemia. 2023 Sep 1;23:S241-2.
Panda T, Rainchwar S, Singh R, Jegan KR, Goswami S, Pillai RH, Kakkar D, Soni M, Singh A, Halder R, Bhurani D. ALL-090 Acute Lymphoblastic Leukemia With t (1; 19)(q23; p13)/TCF3-PBX1 in Adolescents and Adults as a Poor Prognostic Marker of Long-Term Outcome: An Indian Tertiary Care Center Experience. Clinical Lymphoma Myeloma and Leukemia. 2023 Sep 1;23:S239.
Panda T, Rainchwar S, Singh R, Jegan KR, Goswami S, Pillai RH, Kakkar D, Soni M, Singh A, Halder R, Bhurani D. ALL-090 Acute Lymphoblastic Leukemia With t (1; 19)(q23; p13)/TCF3-PBX1 in Adolescents and Adults as a Poor Prognostic Marker of Long-Term Outcome: An Indian Tertiary Care Center Experience. Clinical Lymphoma Myeloma and Leukemia. 2023 Sep 1;23:S239.
Rainchwar S, Panda T, Singh R, Jegan KR, Goswami S, Pillai RH, Kakkar D, Soni M, Singh A, Halder R, Ahemad R. ALL-215 Improved Outcomes of Acute Lymphoblastic Leukemia (ALL) in Adolescent and Young Adults (AYA) Treated With Modified COG0232, a Paediatric-Inspired Intensive Regimen. Clinical Lymphoma Myeloma and Leukemia. 2023 Sep 1;23:S241-2.
Rainchwar S, Singh R, Patra PC, Halder R, Agrawal N. Wernicke’s Encephalopathy: A Rare but Avoidable Neurological Complication Associated with Allogeneic Stem Cell Transplant. Int J Blood Res Disord. 2023;10:091.
Halder R, Talaulikar D, Singh R, Menon N, Folbs B, Mehta P, Kapoor J, Khushoo V, Verma M, Bansal N, Agrawal N. Temporal Changes in SARS-CoV-2 Infection Pattern in Patients Admitted with Hematological Diseases—A Single Center Experience from North India. Hemato. 2023 Mar 14;4(1):100-11.
Mishra V, Yadav PS, Singh R, Rainchwar S, Palatty RJ, Jha K, Panda T, Halder R, Agrawal N, Bhurani D. An observational comparative study to determine the quality of life in transfusion dependent thalassemia patients on low dose thalidomide therapy vs standard care of treatment. Pediatric Hematology Oncology Journal. 2023 Jan 1;8(4):S75.
Singh R, Halder R, Verma M, Mehta P, Agrawal N, Ahmed R, Bhurani D. Hypomethylating Agent Maintenance for Favorable and Intermediate Risk Acute Myeloid Leukemia. 2022 Nov 15;140(Supplement 1):11713-5.
Verma M, Halder R, Singh R, Mehta P, Agrawal N, Ahmed R, Bhurani D. Retrospective Study of Treatment Free Remission in Patients with Chronic Myeloid Leukaemia (CML) Treated at Tertiary Care Oncology Centre from India. Blood. 2022 Nov 15;140(Supplement 1):12222-.
Singh R, Halder R, Kapoor J, Verma M, Mehta P, Agrawal N, Ahmed R, Bhurani D. An Observational Prospective Study of Dasatinib 50mg Daily As Frontline Therapy in Newly Diagnosed Chronic Myeloid Leukemia Patients in Chronic Phase. 2022 Nov 15;140(Supplement 1):12197-9.
Agrawal N. An ‘Uncommon early lineage switch’in an MLL rearranged adult B-lineage Acute Lymphoblastic Leukemia to Mixed-phenotypic acute leukemia (B/Myeloid). IJ Clin Img and med Rew. 2021;1(1):1003.
Agrawal N. Acute pancreatitis in Thalassemia post allo-geneic stem cell transplant with Cyclosporine-A as a possible etiology: a report of two cases. IJ Clin Img and med Rew. 2021;1(1):1008.
Shaikh MR, Mehta P, Mirgh SP, Halder R, Agrawal N, Khushoo V, Ahmed R, Folbs B, Pratihast D, Bansal N, Bhurani D. Individualized AML Induction with Venetoclax Based Therapy in Unfit Treatment Naïve Patients Aged≤ 60 Years: A Real World Perspective from India. 2021 Nov 23;138:4417.
Halder R, Malik R, Aggarwal KC, Nair D, Sharma S. Clinical Profile of Bacterial Meningitis in Children and Comparative Inter-Alia Analysis of Various Microbiological Tests. Journal of Child Science. 2020 Jan;10(01):e38-44.
Zaheir AS, Halder R, Nair RR, Singh PK, Bhar VS, Gambhir I, Zaheir NA. Proteoglycan induced coagulopathy in myeloma–a rare phenomenon. Leukemia & Lymphoma. 2021 Jan 28;62(2):492-4.
Miller AE, Chitnis T, Cohen BA, Costello K, Sicotte NL, Stacom R. Autologous hematopoietic stem cell transplant in multiple sclerosis: recommendations of the National Multiple Sclerosis Society. JAMA neurology. 2021 Feb 1;78(2):241-6.
Halder R, Mishra P, Aggarwal M, Mannivanan P, Dhawan R, Seth T, Tyagi S, Mahapatra M, Pati HP, Saxena R. Outcomes of paroxysmal nocturnal hemoglobinuria in the pediatric age group in a resource‐constrained setting. Pediatric Blood & Cancer. 2020 Apr;67(4):e27712.
Halder R, Seth T, Chaturvedi P, Mahapatra M, Pati HP, Tyagi S, Saxena R. Utility of serial procalcitonin measurement in management of febrile neutropenia in a resource constrained setting.
Halder R, Malik R, Aggarwal KC, Nair D, Sharma S. Clinical Profile of Bacterial Meningitis in Children and Comparative Inter-Alia Analysis of Various Microbiological Tests. Journal of Child Science. 2020 Jan;10(01):e38-44.
Halder R, Seth T, Mahapatra M, Chaturvedi P, Pati HP, Saxena R. PB2041 Utility Of Inflammatory Markers In Distinguishing Various Infective Etiologies Of Fever In Febrile Neutropenic Patients. 2019 Jun 1;3(S1):921.
Mirgh SP, Mahapatra M, Seth T, Dhawan R, Aggarwal M, Saxena R, Pati H, Kothari S, Halder R. PB2186 Impact Of Cytogenetic Abnormalities On Response In A Cohort Of Indian Multiple Myeloma Patients–Is 13q Deletion The New 17p In Disguise?. HemaSphere. 2019 Jun 1;3(S1):981.
Malik R, Halder R. Postvaricella Bacterial Endocarditis Complicating as Cerebral Abscess—A Case Report. Journal of Pediatric Infectious Diseases. 2015 Sep;10(03):089-92.
Halder R, Kashyap R. Hodgkin Lymphoma With Central Nervous System Disease at Primary Presentation. Pediatric Blood & Cancer. 2016 Jan 27;63(6):1130-.
Malik R, Mohapatra JN, Kabi BC, Halder R. Hydroxy Cholecalciferol Levels in Infants with Hypocalcemic Seizures. J Nutr Food Sci. 2014 Jan 1;4(3):1073-5.