Dr. Sandeep Jain

Professional Journey

Achievements

• Started unrelated and haploidentical bone marrow transplant in Pediatric Oncology unit
• Implementation of standard of care international protocols for all childhood cancers

Awards

• GNH scholarship SIOP 2023
• Researcher of the Year award 2019; (RGCON 2019)
• Best Paper for quality improvement: Singapore St Jude- Viva forum 2018
• Young Doctor Award, 2011(RGCON 2011)
• Chairman Appreciation Award, September 2015 (Institute Foundation Day)

Publications

• Jain S, Teotia N, Malhotra P, Kapoor G. Single versus two doses of palonosetron for prevention of chemotherapy-induced nausea and vomiting in children: a double-blind placebo controlled randomized study. J Chemother. 2025 Apr 9:1-9. doi: 10.1080/1120009X.2025.2488598. Epub ahead of print. PMID: 40205780.
• Malhotra, P., Jain, S., Sharma, R., Pahuja, A., Goyal, R., Sharma, A., & Kapoor, G. (2025). A case control analysis of pattern and risk factors for pulmonary dysfunction amongst childhood cancer survivors: a single centre study from a low-middle income setting. Pediatric Hematology and Oncology, 42(2), 104–114. https://doi.org/10.1080/08880018.2025.2456934
• Banwait DK, Arora PR, Mahajan A, Dinand V, Jain S, (2023) Barriers to Accessing Fertility Preservation in Adolescents with Hodgkin Lymphoma in India, Pediatric Hematology and Oncology, DOI: 10.1080/08880018.2023.2218444
• Mishra V, Jain S, Anand V, Malhotra P, Tejwani N, Kapoor G. Impact of minimal residual disease on relapse in childhood acute lymphoblastic leukemia: Lessons learnt from a tertiary cancer center in India [published online ahead of print, 2023 Mar 17]. Pediatr Hematol Oncol. 2023;1-12. doi:10.1080/08880018.2023.2186553
• Kalra, M., Bakhshi, S., Singh, M., Seth, R., Verma, N., Jain, S., (2023). Response assessment by positron emission tomography-computed tomography as compared with contrast-enhanced computed tomography in childhood Hodgkin lymphoma can reduce the need for radiotherapy in low- and middle-income countries. Pediatric blood & cancer, 70(2), e30091. https://doi.org/10.1002/pbc.30091
• Mahajan A, Bakhshi S, Singh M, et al. Empirical Antitubercular Treatment for Lymphadenopathy: Are We Missing Lymphoma? [published online ahead of print, 2022 Jun 23]. Indian J Pediatr. 2022;10.1007/s12098-022-04180-6. doi:10.1007/s12098-022-04180-6
• Agarwal A, Kapoor G, Jain S, Malhotra P, Sharma A. Metabolic syndrome in childhood cancer survivors: Delta BMI a risk factor in lower-middle-income countries. Support Care Cancer. 2022;30(6):5075-5083. doi:10.1007/s00520-022-06910-0
• Priyanka, S., Sandeep, J., Gauri, K., & Gayatri, V. (2022). Dual-Energy X-Ray Absorptiometry and Anthropometry for Assessment of Nutritional Status at Diagnosis in Children with Cancer: A Single-Center Experience from India. South Asian journal of cancer, 11(2), 164–171. https://doi.org/10.1055/s-0042-1757860
• Mishra V, Jain S, Malhotra P, Durga G, Kapoor G. Primary orbital yolk sac tumor in an infant: A rare entity. Indian J Pathol Microbiol [Epub ahead of print] [cited 2022 Jun 25]. Available from: https://www.ijpmonline.org/preprintarticle.asp?id=345894
• Jain S, Bakhshi S, Seth R, et al. Risk based, and response adapted radiation therapy for children and adolescents with newly diagnosed advanced stage Hodgkin lymphoma treated with ABVD chemotherapy: a report from the Indian pediatric oncology group study InPOG-HL-15-01 [published online ahead of print, 2021 Dec 9]. Leuk Lymphoma. 2021;1-8. doi:10.1080/10428194.2021.2012659
• A Mahajan, M. Singh, S. Bakhshi, S. Jain et al Treating early-stage Hodgkin lymphoma in resource-limited settings: InPOG-HL-15-01 experience [published online ahead of print, 2021 Jul 22]. Pediatr Blood Cancer. 2021; e29219. doi:10.1002/pbc.29219
• Mahajan, A, Bhakshi S, Seth R, Verma, N, Mandal, P, Singh, M, Jain S et al Hodgkin Lymphoma in Children Under 5 Years: Do They Behave Differently? Journal of Pediatric Hematology/Oncology: May 2022 – Volume 44 – Issue 4 – p 186-190 doi: 10.1097/MPH.0000000000002423
• Classical Hodgkin Lymphoma Presenting as Cutaneous and Soft Tissue Mass Lesion: An Enigmatic Presentation Posing a Diagnostic Challenge—A Case Report and Review of Literature Indian J Med Paediatr Oncol DOI: 10.1055/s-0041-1740441
• Malhotra, P., Jain, S., Agarwal, A. et al. Incidence and Prognostic Impact of TCF3-PBX1 Fusion in Childhood Acute Lymphoblastic Leukemia: A Single Centre Experience. Indian J Hematol Blood Transfus (2021). https://doi.org/10.1007/s12288-021-01452-7
• Malhotra, P., Kapoor, G., Jain, S. et al. Obesity and Sarcopenia in Survivors of Childhood Acute Lymphoblastic Leukemia. Indian Pediatr 58, 436–440 (2021). https://doi.org/10.1007/s13312-021-2213-7
• Pruthi, M., Virk, J.S., Tiwari, A. Jain S et al. Primary Fibular Sarcomas: Do They Behave Differently? An Institutional Review of 14 Patients. Indian J Surg Oncol (2021). https://doi.org/10.1007/s13193-021-01286-9
• Teotia, N., Jain, S., Kapoor, G. et al. Olanzapine for the Treatment of Breakthrough Vomiting in Children Receiving Moderate and High Emetogenic Chemotherapy. Indian Pediatr 57, 1069–1070 (2020). https://doi.org/10.1007/s13312-020-2038-9
• Verma P, Jain S, Kapoor G, Tripathi R, Sharma P, Doval DC. IAP chemotherapy regimen is a viable and cost-effective option in children andaAdolescents with osteosarcoma: A comparative analysis with MAP Regimen on toxicity and survival [published online ahead of print, 2020 Sep 11]. J Pediatr Hematol Oncol. 2020;10.1097/
• Kapoor G, Jain S. Choice of Local therapy in children with Ewing sarcoma. Indian Pediatr. 2020;57(6):503-504.
• Arora R, Dinand V, Kalra M, Jain S et al Challenges and lessons learnt in setting up the first collaborative multicentre prospective clinical trial in childhood cancer in India. Pediatric Hematology Oncology Journal, ISSN: 2468-1245
• Kaur A Malhotra P, Jain S, Kapoor G A Case of Burkitt’s Lymphoma in a Child Presenting with Obstructive Jaundice and Requiring Surgical Intervention
• Vyas, C., Jain, S., Kapoor, G. Experience with generic pegylated L-asparaginase in children with acute lymphoblastic leukemia and monitoring of serum asparaginase activity Pediatr Hematol Oncol. 2018 Aug-Sep;35(5-6):331-340.
• Jain S, Kapoor G, Koneru S, Vishwakarma G. A randomized, open-label non-inferiority study to compare palonosetron and ondansetron for prevention of acute chemotherapy-induced vomiting in children with cancer receiving moderate or high emetogenic chemotherapy. Support Care Cancer.2018 Sep;26(9):3091-3097.
• Malhotra P, Jain S, Kapoor G Incidence and Risk Factors For Hypertension During Childhood Acute Lymphoblastic Leukemia Therapy. Indian Pediatr. 2018 Oct 15;55(10):877-879.
• Malhotra P, Jain S, Kapoor G Symptomatic Cerebral Sinovenous Thrombosis Associated With L-Asparaginase In Children With Acute Lymphoblastic Leukemia: A Single Institution Experience Over 17 Years. J Pediatr Hematol Oncol. 2018 Oct;40(7):e450-e453. doi: 10.1097/MPH.0000000000001127
• Bhethanabhotla S, Jain S, Kapoor G, Mahajan A, Chopra A, Vishnubhatla S, Bakhshi S. Outcome of Pediatric Advanced Hodgkin Lymphoma treated with ABVD and Predictors of Inferior Survival: A Multicenter Study of 186 patients Leuk Lymphoma. 2017 Jul;58(7):1617-1623.
• Jain S, Mehta A, Kapoor G, Bhurani D, Jain S et al Evaluating New Markers for Minimal Residual Disease Analysis by Flow Cytometry in Precursor B Lymphoblastic Leukemia J Hematol Blood Transfus (2017). doi:10.1007/s12288-017-0845-5.
• Vyas, C., Jain, S., Kapoor, G. Therapy Related AML/MDS Following Treatment for Childhood Cancer: Experience from a Tertiary Care Centre in North India J Hematol Blood Transfus (2017). doi:10.1007/s12288-017-0845-5
• Jain S, Jain S, Kapoor G, Virmani A, Bajpai R. No impact of disease and its treatment on bone mineral density in survivors of childhood acute lymphoblastic leukemia. Pediatr Blood Cancer. Pediatr Blood Cancer, 64: n/a, e26271. doi:10.1002/pbc.26271
• Koneru S, Jain S, Kapoor G. in A rare case of Acute Megakaryoblastic leukemia with orbital chloroma a non-Down syndrome child [Accepted for publication in Asian journal of oncology journal]
• Jain S, Kapoor G, Bajpai R. ABVD-Based Therapy for Hodgkin Lymphoma in Children and Adolescents: Lessons Learnt in a Tertiary Care Oncology Center in a Developing Country. Pediatr Blood Cancer. 2016 Jun;63(6):1024-30.
• Gupta A, Kapoor G, Jain S, Bajpai R. Absolute Lymphocyte Count Recovery Independently Predicts Outcome in Childhood Acute Lymphoblastic Leukemia: Experience from a Tertiary Care Cancer Centre of a Developing Country. J Pediatr Hematol Oncol. 2015 Apr;37(3):e143-9
• Kapoor G, Sachdeva N, Jain S. Epidemiology of bacterial isolates among pediatric cancer patients from a tertiary care oncology centre in North India. Indian J Cancer. 2014 Oct-Dec;51(4):420-4.
• Malhotra P, Jain S, Kapoor G. Cavernous Sinus Thrombosis with Occlusion of Internal Carotid Artery in a Child with Acute Lymphoblastic Leukemia Pediatr Neurol. 2015 Dec;53(6):541-2.
• Jain S, Kapoor G . Chemotherapy in Osteosarcoma: Current Strategies. March 2016 2(1):27-32.
• Jain S, Kapoor G, Invasive Aspergillosis in Children With Acute Leukemia at a Resource-limited Oncology Center. J Pediatr Hematol Oncol. 2014 Mar 28. [Epub ahead of print]
• Gupta A, Jain S, Kapoor G. Successful outcome of mucormycosis in two children on induction therapy for acute lymphoblastic leukemia. Indian J Med Paediatr Oncol. 2013 Oct;34(4):313-6.
• Tiwari A, Jain S, Mehta S et al. Limb salvage surgery for osteosarcoma- early results in indian patients. Indian J Orthop 2014;48:266-72.
• Jain S, Kapoor G. How to treat relapsed acute lymphoblastic leukemia: transplant vs. conventional chemotherapy. Indian J Pediatr. 2013 Oct;80(10):846-52.
• Das K, Jain S, Chichra A, Gupta H, Kapoor G. Non-hematological tumors of head and neck region in the pediatric age group in a tertiary care cancer center Pediatric Surgery International 2011, Volume 27, Issue 9, pp 919–923
• Jain, S., Kapoor, G. (2014). Imatinib-associated massive upper gastrointestinal hemorrhage and hepatic encephalopathy in a child with Philadelphia positive acute lymphoblastic leukemia: A case report and review of the literature. South Asian Journal of Cancer, 3(4), 234–235.
• Verma P, Jain, S., Kapoor, G. Complete response with crizotinib in two children with chemotherapy resistant neuroblastoma (Accepted for publication in South Asian Journal of Cancer)
• Tiwari, A., Gupta, H., Jain, S. and Kapoor, G. Outcome of multimodality treatment of Ewing’s sarcoma of the extremities. Indian Journal of Orthopaedics. 2010; 44, 378-383.
• Jain, S. and Kapoor, G. Chemotherapy in Ewing’s sarcoma. Indian Journal of Orthopaedics. 2010; 44, 369-377.
• Yadav, S. P., Kharya, G., Mohan, N., Sehgal, A., Bhat, S., Jain, S., Kapoor, G. and Sachdeva, A. Langerhans cell histiocytosis with digestive tract involvement. Pediatric Blood & Cancer. 2010; 55, 748-753.
• Jain S, Kapoor G, Severe life-threatening neurotoxicity in a child with acute lymphoblastic leukemia receiving posaconazole and vincristine. .Pediatr Blood Cancer. 2010;54(5):783.
• Jain S, Naithani R, Kapoor G, Nath Triloki, L-asparaginase induced severe hypertriglyceridemia in acute lymphoblastic leukemia with 11q23 abnormality Leuk Res. Volume 33, Issue 11:194.
• Saha Rajat, Jain S, Naithani R, Kapoor G, Chemotherapy- induced palmoplantar erythrodysesthesia in a child with Burkitt lymphoma. Pediatr Blood Cancer. 2009 Oct; 53(4):682.