DONATEPancreatic Cancer Treatment
Overview
Pancreatic cancer occurs when abnormal cells within the pancreas begin to multiply uncontrollably, forming a malignant tumour that can invade nearby tissues or spread to different sites. At RGCIRC (Rajiv Gandhi Cancer Institute & Research Centre), our specialists have extensive experience in managing all stages of pancreatic cancer using evidence-based treatment protocols, advanced surgical options, and comprehensive care pathways. The team focuses on accurate staging, personalised treatment planning, and supportive care that prioritises patient comfort and safety. With facilities equipped for neoadjuvant therapy, complex resections, minimally invasive surgery, and post-treatment rehabilitation, RGCIRC ensures holistic and reliable care for individuals seeking specialised pancreatic cancer treatment and management in India.
What is Pancreatic Cancer?
Pancreatic cancer is a malignant tumour that originates in the cells of the pancreas, an organ responsible for producing digestive enzymes and regulating blood sugar through hormone secretion. The disease begins when pancreatic cells acquire genetic mutations that lead to uncontrolled growth, forming a malignant tumour that can invade nearby tissues or spread to distant organs.
Most pancreatic cancers arise from the exocrine component of the pancreas, particularly the ductal cells, while a smaller proportion develops from the endocrine (neuroendocrine) cells that produce hormones. Because the pancreas is located deep within the abdomen, early-stage tumours often do not cause noticeable symptoms, making timely clinical evaluation and high-quality imaging essential for accurate detection and staging.
Types of Pancreatic Cancer
Pancreatic cancer is not a single disease. Tumours in the pancreas can arise from different types of cells, and each behaves differently and may need a different treatment approach. Broadly, pancreatic cancers are grouped into two main categories.
Exocrine tumours
Most pancreatic cancers are exocrine tumours. These usually start in the ducts that carry digestive enzymes from the pancreas to the small intestine. The most common type is pancreatic ductal adenocarcinoma. Exocrine tumours, especially pancreatic ductal adenocarcinoma, are known to behave aggressively, so treatment is usually planned without delay once the diagnosis is confirmed.
Neuroendocrine tumours
Pancreatic neuroendocrine tumours (also called pancreatic NETs) develop from hormone-producing cells in the pancreas. These tumours are less common than exocrine cancers and may grow more slowly in some cases. Some NETs produce hormones that cause specific symptoms, while others remain “non-functioning” and are found incidentally on scans. Treatment planning takes into account the tumour’s size, grade, hormone activity, and whether it has spread.
Most pancreatic cancers arise from the exocrine component of the pancreas, particularly the ductal cells, while a smaller proportion develops from the endocrine (neuroendocrine) cells that produce hormones. Because the pancreas is located deep within the abdomen, early-stage tumours often do not cause noticeable symptoms, making timely clinical evaluation and high-quality imaging essential for accurate detection and staging.
Pancreatic Cancer Symptoms
Jaundice-related symptoms
- Yellowing of the skin and eyes
- Dark urine
- Light-coloured or greasy stools
- Itchy skin
Digestive and appetite-related symptoms
- Nausea or vomiting
- Gas, bloating, or indigestion
- Reduced appetite
- Unexplained weight loss
Pain-related symptoms
- Upper abdominal pain
- Pain that spreads to the middle of the back
Systemic and metabolic changes
- Fatigue
- New-onset diabetes or unexpected changes in blood sugar
- Blood clots without a clear cause
What Causes Pancreatic Cancer?
- Genetics and family history: Inherited genetic changes, such as BRCA mutations or a family history of pancreatic or related cancers, can increase risk.
- Smoking: Tobacco use is one of the most well-established risk factors for pancreatic cancer.
- Chronic pancreatitis: Long-term inflammation of the pancreas, particularly when associated with hereditary causes, may raise the risk of cancer.
- Diabetes: Long-standing diabetes and sudden changes in blood sugar control can be linked with an increased risk.
- Obesity and lifestyle factors: Excess body weight, low physical activity, and certain dietary patterns may influence pancreatic cancer risk.
- Age: The likelihood of pancreatic cancer increases with age, most commonly after 55.
Different Stages of Pancreatic Cancer
Staging describes how far pancreatic cancer has spread at the time of diagnosis. This information helps doctors determine the most suitable treatment options and understand how the disease is likely to behave. Pancreatic cancer is generally classified into the following stages:
Stage 0: Abnormal cells are present in the lining of the pancreatic ducts but have not invaded deeper tissues. This stage is also called carcinoma in situ.
Stage I: The tumour is confined to the pancreas and has not spread to nearby structures or lymph nodes. Tumours may be small, but treatment decisions depend on their exact size and location.
Stage II: The tumour remains within or around the pancreas but may involve nearby tissues or a limited number of lymph nodes. Surgery may still be considered depending on the extent of involvement.
Stage III: The cancer has spread to nearby major blood vessels or multiple lymph nodes, making surgery more challenging. In many cases, treatment begins with chemotherapy or chemoradiotherapy to help control the disease and assess operability.
Stage IV: The cancer has spread to distant organs such as the liver or lungs. Treatment focuses on controlling symptoms, slowing disease progression, and supporting quality of life.
How is Pancreatic Cancer Diagnosed at RGCIRC?
Diagnosing pancreatic cancer involves a combination of detailed imaging studies, laboratory tests, and tissue evaluation. Because early symptoms can be subtle, doctors use multiple diagnostic tools to confirm the diagnosis, understand the extent of the disease, and plan the most suitable treatment. At RGCIRC, diagnostic evaluation typically includes the following methods:
CT Scan
A contrast-enhanced CT scan provides detailed images of the pancreas and surrounding structures. It helps identify the size of the tumour, its relation to nearby vessels, and possible spread.
MRI
MRI offers high-resolution images of soft tissues and helps evaluate the bile ducts, liver, and pancreas, especially when additional clarity is required.
PET Scan
A PET or PET-CT scan detects active cancer cells throughout the body. It helps assess metastasis and guides treatment planning.
Blood Tests (CA 19-9)
CA 19-9 is a blood marker that may rise in pancreatic cancer, as well as in some non-cancerous conditions. Because it is not specific enough to confirm the disease on its own, doctors use it together with scans and tissue examination to support diagnosis and track treatment progress.
Endoscopic Ultrasound (EUS)
EUS uses an endoscope with an ultrasound probe to obtain detailed images from inside the digestive tract. It allows doctors to visualise the tumour closely and take tissue samples if needed.
Biopsy
A biopsy confirms the diagnosis by examining tissue under a microscope. Samples may be obtained during EUS or through image-guided techniques, depending on the tumour’s location.
Advanced Pancreatic Cancer Treatment Available at RGCIRC
Pancreatic cancer treatment requires a coordinated, multidisciplinary approach involving surgical oncology, medical oncology, radiation oncology, and supportive care specialists. At RGCIRC, treatment is personalised according to the stage of the disease, tumour location, overall health, and whether the cancer can be safely removed with surgery. The centre offers a full spectrum of evidence-based cancer treatments, including:
Surgical Options (Pancreatic Cancer Surgeries)
Surgery offers the best chance of long-term control when the tumour can be removed completely. The type of procedure depends on where the cancer is located within the pancreas.
Whipple procedure (Pancreatoduodenectomy)
This surgery is performed for tumours in the head of the pancreas. It involves removing the pancreatic head along with parts of the duodenum, bile duct, and, when needed, a portion of the stomach. Reconstruction restores normal digestive flow.
Distal pancreatosplenectomy
Used for tumours in the body or tail of the pancreas, this procedure removes the affected part of the pancreas and the spleen.
Total pancreatectomy
In selected cases, the entire pancreas may need to be removed when the tumour involves the whole gland or multiple regions. Patients receive long-term guidance on managing digestion and blood sugar after this operation.
Minimally invasive or robotic pancreatic surgeries
For appropriately selected patients, minimally invasive or robotic approaches may be offered to support faster recovery, reduced postoperative discomfort, and shorter hospital stay.
Palliative surgeries for advanced cases
When the tumour cannot be removed, surgery may help relieve symptoms such as jaundice or digestive obstruction, improving comfort and quality of life.
Specialised vascular resections (for select cases)
For some locally advanced tumours, surgery may include reconstruction of nearby veins after neoadjuvant chemotherapy or chemoradiotherapy. These procedures are considered only when they can be done safely as part of an attempt at complete tumour removal.
Therapy-Based Pancreatic Cancer Treatment Options
Medication-based and non-surgical treatments play an essential role in managing pancreatic cancer, whether used before surgery, after surgery, or when surgery is not possible. Therapy based pancreatic cancer treatment options include:
Chemotherapy
Chemotherapy may be used before surgery (neoadjuvant) to shrink the tumour, after surgery (adjuvant) to reduce the risk of recurrence, or as the main treatment for advanced or metastatic disease.
Radiation therapy
Radiation therapy, sometimes combined with chemotherapy, helps control tumour growth in locally advanced disease and may improve the chances of surgical removal in select cases.
Targeted therapy
Certain pancreatic neuroendocrine tumours or cancers with specific genetic changes may respond to targeted drugs. Eligibility depends on detailed molecular testing.
Pain management and symptom control
Pain-relief procedures, nerve blocks, and supportive therapies help improve comfort and daily functioning throughout treatment.
Why RGCIRC is a Trusted Pancreatic Cancer Treatment Hospital in Delhi, India
Pancreatic cancer care requires experience, precision, and a coordinated medical team that understands the complexities of the disease. At Rajiv Gandhi Cancer Institute & Research Centre, we combine advanced technology with compassionate, evidence-based care to support patients at every stage of their treatment journey. Our focus is always on safety, clarity, and personalised guidance. We provide:
India’s Leading Oncology Specialists
Our team includes highly experienced surgical, medical, and radiation oncologists who specialise in pancreatic and gastrointestinal cancers. Their expertise helps ensure that each treatment plan is designed thoughtfully and tailored to individual needs.
High-success Surgical Outcomes
We follow established, evidence-based protocols and use advanced surgical techniques to support safe operations and improved recovery, especially in complex or locally advanced tumours.
Advanced Robotic Surgery and Minimally Invasive Techniques
RGCIRC offers access to modern minimally invasive and robotic platforms, which may benefit select patients by reducing discomfort and supporting quicker return to routine activities.
Multidisciplinary Tumour Board Approach
Each case is reviewed through a collaborative process that brings together specialists from different disciplines. This ensures that every treatment decision is backed by collective expertise and the latest clinical guidelines.
State-of-the-art Diagnostic and Treatment Facilities
From high-resolution imaging and PET-CT to advanced radiotherapy systems and modern operating suites, our facilities support accurate diagnosis and comprehensive cancer care.
Commitment to Research and Continual Improvement
RGCIRC actively participates in clinical research and collaborative studies that focus on improving cancer detection, treatment outcomes, and supportive care. This commitment ensures that patients benefit from updated knowledge, evolving evidence, and treatment practices aligned with global standards.
Integrated Nutrition, Psychology, and Rehabilitation Support
Pancreatic cancer treatment affects many aspects of health. Our dedicated support teams offer nutrition guidance, psychological counselling, and physiotherapy to help patients maintain strength and overall well-being throughout treatment.
Affordable and Transparent Treatment Packages
We provide clear, transparent cost structures and work with patients and families to plan treatment in a way that is both medically sound and financially considerate.
Recovery & Life After Pancreatic Cancer Treatment
Recovery after pancreatic cancer treatment varies from person to person and depends on the type of surgery, the stage of the disease, and the therapies received. The focus during this phase is to help patients regain strength, manage symptoms, and adapt to changes in digestion and metabolism. At RGCIRC, recovery support continues long after the initial treatment ends, with dedicated services designed to promote long-term well-being. We offer:
Nutrition Guidance
Nutrition plays an important role in recovery, especially after pancreatic surgery. Dieticians provide tailored plans that help manage digestion, maintain weight, and support energy levels. Enzyme supplements may be recommended when needed to help with food absorption.
Pain Management
Specialists help manage discomfort through medications, nerve blocks, and supportive therapies. Pain-relief strategies are adjusted over time as recovery progresses.
Follow-up Schedules
Regular follow-up visits allow doctors to monitor healing, check for treatment side effects, and look for any signs of recurrence. These appointments may include physical examinations, blood tests such as CA 19-9, and periodic imaging.
Emotional and Psychological Support
Coping with cancer can be overwhelming. Psychologists and counsellors at RGCIRC provide emotional support, helping patients and families navigate stress, anxiety, and lifestyle changes during and after treatment.
Long-term Monitoring for Recurrence
Ongoing surveillance is an essential part of pancreatic cancer care. The clinical team guides patients on what to expect, when to seek help, and how to maintain overall health during survivorship.
Book an Appointment at RGCIRC: One of the Leading Pancreatic Cancer Treatment Hospitals in Delhi, India
Pancreatic cancer can feel overwhelming, especially when symptoms appear suddenly or a diagnosis comes without warning. Timely evaluation and access to experienced specialists play an important role in improving outcomes and ensuring that every treatment decision is well informed. At Rajiv Gandhi Cancer Institute & Research Centre, our team is committed to guiding patients and families with clarity, compassion, and evidence-based care at every step.
To consult a cancer specialist at Rajiv Gandhi Cancer Institute & Research Centre, call +91-11-47022222, +91 11 27051037 or fill out our contact form.
Frequently Asked Questions (FAQs)
Q: Which hospital is best for pancreatic cancer treatment in Delhi?
A: Specialised cancer centres such as RGCIRC offer comprehensive pancreatic cancer care, advanced diagnostics, and multidisciplinary treatment planning, making them a preferred option for patients seeking expert evaluation in Delhi.
Q: What is the survival rate of pancreatic cancer in India?
A: The survival rate varies based on the stage at diagnosis, tumour type, and overall health. Early detection and access to experienced specialists can help improve outcomes.
Q: How is pancreatic cancer detected?
A: Doctors use imaging tests such as CT, MRI, and PET-CT scans, along with blood markers such as CA 19-9 and confirmatory biopsies, to diagnose and stage pancreatic cancer.
Q: What are the treatment options for stage 4 pancreatic cancer?
A: Treatment for stage 4 disease focuses on controlling symptoms, slowing progression, and improving quality of life through chemotherapy, targeted therapy when appropriate, and supportive care.
Q: What tests are used to check for pancreatic cancer near me?
A: Common tests include CT scans, MRI, PET-CT, CA 19-9 blood tests, and endoscopic ultrasound. These are available at specialised cancer hospitals in Delhi.
Q: Is pancreatic cancer hereditary?
A: Some cases involve inherited genetic mutations. Doctors may recommend genetic counselling or testing if there is a strong family history.
Q: What is the cost of pancreatic cancer treatment in India?
A: Costs depend on the stage of the disease, type of treatment, and duration of care. Hospitals such as RGCIRC offer transparent packages and guide families on financial planning.
Q: Can pancreatic cancer cause diabetes?
A: Yes. New-onset diabetes or sudden changes in blood sugar may occur due to pancreatic cancer or its treatment.
Q: What foods should a pancreatic cancer patient avoid?
A: Diets are tailored individually, but doctors may advise limiting high-fat or hard-to-digest foods. A dietician provides personalised recommendations based on the patient’s condition.
Q: Where can I find the best pancreatic cancer specialists near me?
A: Specialised surgical, medical, and radiation oncologists at centres such as RGCIRC in Delhi provide expert care for pancreatic cancer.
